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目的:观察中西医结合治疗强直性脊柱炎的临床疗效。方法:入选强直性脊柱炎患者随机分为治疗组(65例)和对照组(58例)。对照组使用非甾体类消炎药、慢作用药,治疗组在对照组基础上加用中医综合疗法。分别于治疗后3个月、6个月观察治疗前后临床症状、关节功能活动程度、扩胸试验、Schober’s氏试验、指地试验、枕墙距的变化;实验室检查血沉(ESR)、C-反应蛋白(CRP)。结果:治疗后3个月、6个月,2组各观察指标与治疗前比较,差异有统计学意义(P<0.05),2组间总有效率比较差异有统计学意义(P<0.05),且治疗组不良反应发生率、复发率低于对照组,差异有统计学意义(P<0.05)。结论:中西医结合治疗强直性脊柱炎能明显改善强直性脊柱炎患者的症状、体征,提高患者的生活质量。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of ankylosing spondylitis. Methods: The patients with ankylosing spondylitis were randomly divided into treatment group (65 cases) and control group (58 cases). The control group used non-steroidal anti-inflammatory drugs, slow-acting drugs, the treatment group in the control group based on the use of traditional Chinese medicine combined therapy. The clinical symptoms, the degree of joint functional activity, the chest expansion test, the Schober’s test, the finger test and the change of the pillow wall distance were observed at 3 months and 6 months after the treatment respectively. The laboratory test ESR, C- Reactive protein (CRP). Results: After 3 months, 6 months and 2 months of treatment, there were significant differences between the two groups (P <0.05) before and after treatment. There was significant difference in total effective rate between the two groups (P <0.05) , And the incidence of adverse reactions and recurrence in the treatment group was lower than that in the control group, with significant difference (P <0.05). Conclusion: Integrative treatment of ankylosing spondylitis can significantly improve the symptoms and signs of patients with ankylosing spondylitis, improve the quality of life of patients.