原发性胆汁性肝硬化（Primary biliary cirrhosis,PBC）由英国 Addisson和 Gull于1851年首先报道,随后法国的 Hanot于1876年进一步的报道。因本病伴有高胆固醇血症和皮肤黄疣;将其命名为“黄疣性胆汁性肝硬化”。Ahrens等1950年根据本病的病理学和临床特点,命名为:原发性胆汁性肝硬化,沿用 Primary biliary cirrhosis (PBC) was first reported by Addison and Gull in Britain in 1851, followed by Hanot in France in 1876. Because of the disease accompanied by hypercholesterolemia and skin yellow warts; will be named as “yellow warts biliary cirrhosis.” Ahrens other 1950 according to the pathological and clinical features of the disease, named: primary biliary cirrhosis, follow