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开胸狗16只,其中12只狗用电磁流量计测定左冠状动脉回旋支流量、股动脉流量,16只狗中有4只狗测定左心室收缩压和舒张压,静脉滴注复方丹参4克/公斤后,左冠状动脉回旋支流量增加60％,股动脉流量减少1.7％,冠脉阻力降低54.5％,血压下降30％,左心室收缩压和舒张压有轻度下降。本实验结果表明,复方丹参能增加冠脉流量,降低冠脉阻力,降低血压等。复方丹参注射液基本符合改善冠脉循环的要求,是改善冠脉循环的良好药物,可作为用丹参治疗冠心病患者心肌缺血的依据。
Thoracotomy dogs 16, including 12 dogs with electromagnetic flowmeter measurement of left coronary artery collaterals, femoral artery flow, 16 dogs in four dogs measured systolic and diastolic left ventricular systolic pressure, intravenous infusion of compound Salvia 4 grams Kg / kg, left circumflex artery increased 60%, femoral artery flow decreased 1.7%, coronary resistance decreased 54.5%, blood pressure decreased 30%, left ventricular systolic and diastolic blood pressure decreased slightly. The experimental results show that compound Danshen can increase coronary flow, reduce coronary resistance, lower blood pressure and so on. Compound Danshen injection basically meets the requirements of improving coronary circulation, is a good drug to improve coronary circulation, can be used as the basis for the treatment of myocardial ischemia in patients with coronary heart disease.