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出生缺陷可引起死胎、死产,在我国城市新生儿死因中占第一或第二位,也是婴儿死亡之要因。它给母亲、家庭及社会带来痛苦和负担。在各种出生缺陷中,神经管畸形(简称NTD,下同)危害严重,其发生率据国外报导为0.7‰至8.7‰。为了搞好计划生育、围产期保健及优生,加强关于出生缺陷的研究和防治,十分重要。可是迄今国内有关于出生缺陷的研究报导甚少,至于NTD的专门研究报告,更未见到。本研究的目的是收集和分析北京地区NTD的资料,以反映本地区发生情况,并初步查明其流行特征及影响因素,供进一步流行病学病因方面研究时参考。
Birth defects can cause stillbirths and stillbirths, accounting for the first or second place in the deaths of newborns in cities in China and are also the cause of infant mortality. It brings pain and burden to mothers, families and the community. In a variety of birth defects, neural tube defects (referred to as NTD, the same below) are seriously devastating, the incidence reported by foreign countries from 0.7 ‰ to 8.7 ‰. In order to improve family planning, perinatal care and eugenics, it is very important to strengthen research and prevention and control of birth defects. But so far there are few reports on birth defects in China. As for NTD’s special research report, it has never been seen. The purpose of this study is to collect and analyze the data of NTD in Beijing to reflect the occurrence in this area and to tentatively identify its epidemiological characteristics and influencing factors for reference when studying the etiology of further epidemiology.