(一)小白鼠腹部皮肤感染40条日本血吸虫尾蚴,感染时间自3至20分钟不等,5周後解剖,检查成虫数,发现感染尾蚴5分钟的成虫发育率较低(33%),而感染10分钟(45%),15分钟(51%)及20分钟(54%)之差别不显著。 (二)病员经口服吐酒石治疗2周後停药1,2,3或4周解剖,发现余存虫数之差别并不显著。所以可用1周作为比较锑剂疗效试验的停药时间。 (三)对照组及吐酒石270毫克/千克/天剂量组内,雌雄鼠体内余存虫数相差不显著,但在吐酒石1700毫克/千克/天治疗组内,雌鼠体内的余存虫数少於雄鼠体内的虫数。所以实验治疗所用的小白鼠最好是雌雄各半。 (四)吐酒石治疗後大小两级体重鼠体内余存虫数,仅在停药3周组内有显著的差别:其他组内则未见显著差别。 (A) Infection of cercariae of Schistosoma japonicum 40 in the abdomen skin of mice was observed. The infection time ranged from 3 to 20 minutes. After 5 weeks of dissection, the number of adult worms was examined and the rate of adult cercariae 5 minutes was lower (33%). The difference between infection of 10 minutes (45%), 15 minutes (51%) and 20 minutes (54%) was insignificant. (B) patients after oral administration of tartar treatment for 2 weeks after stopping 1, 2, 3 or 4 weeks of anatomy and found that the remaining number of worms is not significant difference. Therefore, one week can be used as a comparison antimony agent efficacy test withdrawal time. (C) Control group and spit tartar 270 mg / kg / day dose group, male and female rats remaining insects difference is not significant, but in 1700 mg / kg / day spit tartar treatment group, the female body more than The number of surviving insects less than the number of male mice. Therefore, the experimental treatment of mice is best male and female half. (4) There were significant differences among the three groups of mice in the two groups after the treatment of spit tartar. There was no significant difference among the other groups.