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目的探讨冠心病患者红细胞分布宽度(RDW)、血清胆红素水平与冠状动脉病变程度的关系。方法选择2012年4月—2015年5月清河中心医院收治的440例临床诊断为冠心病的患者,根据冠状动脉造影结果,将患者分为冠状动脉造影正常组、冠状动脉单支病变组、冠状动脉双支病变组及冠状动脉多支病变组。检测入选者血清总胆红素(TBi L)、直接胆红素(DBi L)、间接胆红素(IBi L)水平、红细胞分布宽度(RDW)。结果单支病变组、双支病变组、多支病变组男性、吸烟、高血压比例、BMI、TG、LDL-C、GLU水平均高于对照组(P<0.05),冠心病3组与对照组的年龄、HGB、Cr、AST比较,差异无统计学意义(P>0.05)。冠心病组RDW高于对照组,TBi L、DBi L、IBi L低于对照组,差异有统计学意义(P<0.05)。结论 RDW、血清TBi L、DBi L、IBi L与冠状动脉病变的严重程度密切相关,可能是冠状动脉病变的预测因素之一。
Objective To investigate the relationship between the width of erythrocyte distribution (RDW) and the serum bilirubin level in patients with coronary heart disease. Methods From April 2012 to May 2015, 440 patients with clinically diagnosed coronary heart disease admitted to Qinghe Central Hospital were divided into two groups according to coronary angiography: normal coronary angiography group, single coronary artery disease group, coronary artery disease group Arterial double-vessel disease group and multiple coronary artery disease group. Participants were tested for TBi L, DBi L, IBi L and RDW. Results The prevalence rates of smoking, hypertension, BMI, TG, LDL-C and GLU in single vessel disease group, double vessel disease group and multivessel disease group were significantly higher than those in control group (P <0.05) There was no significant difference in age, HGB, Cr, AST between the two groups (P> 0.05). Coronary heart disease group RDW higher than the control group, TBiL, DBiL, IBiL lower than the control group, the difference was statistically significant (P <0.05). Conclusion RDW, serum TBiL, DBiL and IBiL are closely related to the severity of coronary artery disease and may be one of the predictors of coronary artery disease.