论文部分内容阅读
目的探讨代谢综合征(MS)及其组分影响心房颤动(简称房颤)患者类型的因素。方法本研究入选2007年1月至2012年4月,在安贞医院心内科住院的房颤患者1 043例。分为2组:阵发性房颤组615例,持续性房颤组428例。比较两组MS与非MS指标,多因素回归分析影响房颤类型的因素。结果 MS组分数量在持续性房颤组显著大于阵发性房颤组(2.3±1.3 vs 2.1±1.3,P<0.01)。持续性房颤组的体重指数显著高于阵发性房颤组(P<0.01)。阵发性房颤组和持续性房颤组非MS相关指标的比较,左房内径、左室射血分数、尿酸差异有显著性(P<0.01),白细胞差异有显著性(P=0.014)。经校正左房内径、左室射血分数、MS组分的数量、白细胞、尿酸,Logistic多因素回归分析显示左房内径(OR=1.125,95%CI=1.096-1.156,P=0.04)、MS组分的数量(OR=1,95%CI=1.017-1.092,P=0.01)、尿酸(OR=1.006,95%CI=1.004-1.008,P=0.045)与持续性房颤患者呈正相关,左室射血分数(OR=0.955,95%CI=0.938-0.972,P=0.01)呈负相关。结论 MS组分的数量、左房内径、左室射血分数、尿酸是阵发性房颤向持续性房颤进展的独立危险因素。
Objective To investigate the factors influencing the type of patients with atrial fibrillation (MS) and its components affected by metabolic syndrome (MS). Methods A total of 1 043 AF patients admitted to Department of Cardiology, Ahn Jung Hospital from January 2007 to April 2012 were enrolled in this study. Divided into two groups: 615 cases of paroxysmal atrial fibrillation group, 428 cases of persistent atrial fibrillation. MS and non-MS indexes were compared between the two groups, and multivariate regression analysis was used to analyze the factors influencing the type of AF. Results The number of MS components in patients with persistent AF was significantly higher than those in patients with AF (2.3 ± 1.3 vs 2.1 ± 1.3, P <0.01). Body mass index in persistent AF group was significantly higher than that in paroxysmal atrial fibrillation group (P <0.01). Compared with non-MS-related indicators in paroxysmal atrial fibrillation group and persistent atrial fibrillation group, the left atrium diameter, left ventricular ejection fraction and uric acid were significantly different (P <0.01), and the difference of leukocyte was significant (P = 0.014) . The left atrial diameter (OR = 1.125, 95% CI = 1.096-1.156, P = 0.04), MS (subscript MS), left ventricular ejection fraction Uric acid (OR = 1.006, 95% CI = 1.004-1.008, P = 0.045) was positively correlated with patients with persistent atrial fibrillation and left ventricular mass was significantly increased with the number of components (OR = 1,95% CI = 1.017-1.092, P = Room ejection fraction (OR = 0.955, 95% CI = 0.938-0.972, P = 0.01) was negatively correlated. Conclusion The number of MS components, left atrium diameter, left ventricular ejection fraction, and uric acid are independent risk factors for progression of paroxysmal atrial fibrillation to persistent atrial fibrillation.