利奈唑胺是第一个用于临床的新型唑烷酮类抗生素,主要用于重症革兰阳性球菌感染。尽管早在2002年获得美国食品药品管理局批准,但其在儿科尤其是新生儿科应用的经验有限。现将我科应用利奈唑胺治疗耐药金黄色葡萄球菌引起的新生儿皮下坏疽1例报道如下。 Linezolid is the first novel oxazolidinone for clinical use and is mainly used in severe Gram-positive cocci infections. Although approved by the U.S. Food and Drug Administration as early as 2002, its experience in pediatric and especially neonatal applications is limited. Now our department of linezolid treatment of drug-resistant Staphylococcus aureus caused by neonatal subcutaneous gangrene reported as follows.