神经鞘瘤为一种起源于周围神经雪旺细胞的肿瘤,多属于良性~([1])。全身各部位均可发生,大部分多发于头颈部(25%~45%)~([2]),发生于耳鼻咽喉者较少见(4%),而发生于鼻窦、翼腭窝联合部位的巨大神经鞘瘤更罕见。我院2014-01-2017-03期间收治鼻-翼腭窝较大的神经鞘瘤5例,均经手术治疗和病理确诊,术后随访6个月~3年均未见复发,现报告如下。1资料与方法1.1临床资料 Schwannoma is a tumor derived from peripheral nerve Schwann cells, mostly benign ~ ([1]). Most parts of the body can occur in the head and neck (25% ~ 45%) ~ ([2]), occurred in the ear and nose and throat less common (4%), occurred in the sinus, pterygopalatine fossa joint Parts of the great schwannoma is more rare. In our hospital from January 2014 to February 2017-03, we treated 5 patients with larger schwannomas in the pterygopalatine fossa, both of them were confirmed by surgery and pathology. No recurrence was found after 6 months to 3 years follow-up. The reports are as follows . 1 Materials and Methods 1.1 Clinical data