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目的比较不同年龄妊娠期高血压疾病(HDCP)患者的围生期结局。方法对173例HDCP患者的临床资料进行回顾性分析,比较不同年龄组患者的妊娠并发症发生情况。结果①≥35岁组HDCP发病率为12.69%(92/725),占同期HDCP的53.18%(92/173),20~34岁组HDCP发病率为5.42%(81/1 494),占同期HDCP的46.82%(81/173),两组比较,差异有统计学意义(P<0.05);②≥35岁组早产率为16.30%(15/92),胎儿生长受限(FGR)为11.96%(11/92),产后出血为10.87%(10/92),新生儿窒息为10.87%(10/92),胎盘早剥为4.35%(4/92);20~34岁组分别为6.17%(5/81)、11.11%(9/81)、7.41%(6/81)、6.17%(5/81)和2.47%(2/81),两组早产发生率比较,差异有统计学意义(P<0.05);其他指标比较,差异无统计学意义(P>0.05);③≥35岁组和20~34岁组不同程度HDCP发生率比较,差异有统计学意义(P<0.05)。结论≥35岁高龄患者轻度、重度子痫期及早产所占比例高于20~34岁患者,应加强围生期管理。
Objective To compare the perinatal outcome of hypertensive disorders of pregnancy (HDCP) at different ages. Methods The clinical data of 173 patients with HDCP were analyzed retrospectively to compare the incidence of pregnancy complications in different age groups. Results The incidence of HDCP was 12.69% (92/725) in the group of ≥35 years, accounting for 53.18% (92/173) of the HDCP in the same period and HDCP incidence was 5.42% (81/1 494) in the group of 20-34 years old, HDCP 46.82% (81/173), the difference between the two groups was statistically significant (P <0.05); ②≥35-year-old premature birth rate was 16.30% (15/92), fetal growth restriction (FGR) was 11.96 (11/92), postpartum hemorrhage was 10.87% (10/92), neonatal asphyxia was 10.87% (10/92), placental abruption was 4.35% (4/92), while those from 20 to 34 years were 6.17 (5/81), 11.11% (9/81), 7.41% (6/81), 6.17% (5/81) and 2.47% (2/81) respectively. There was a statistically significant difference in the incidence of preterm birth between the two groups (P <0.05). There was no significant difference between the other indexes (P> 0.05); ③ The incidence of HDCP in the groups of ≥35 years and 20 ~ 34 years was significantly different (P <0.05) . Conclusions Patients with ≥35 years of age who have mild to severe preeclampsia and preterm birth are higher than those from 20 to 34 years old. Perinatal management should be strengthened.