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目的:探讨出生体重对早产儿视网膜病变(retinopathy of p rematurity,ROP)发生的影响。方法:选择符合入选条件的三级医院6所作为研究医院,设计ROP筛查临床调查表,选择2006年1月1日～2007年12月31日在调查医院新生儿科住院的出生体重<2 000 g的早产儿作为研究对象。结果:①出生体重<2 000 g的早产儿ROP发生率为12.70%,阈值病变发生率为3.56%。②出生体重<1 000 g、1 000～1 249 g、1 250～1 499 g、1 500～1 749 g、1 750～2 000 g的患儿ROP发生率分别为25.00%、21.80%、14.20%、11.40%、7.40%。结论:三级医院出生体重<2 000 g的早产儿ROP发生率是12.70%,阈值病变发生率3.56%。随着体重的降低ROP的发生率升高,程度越严重,出生体重是ROP发生的重要高危因素。
Objective: To investigate the effect of birth weight on the occurrence of retinopathy of prematurity (ROP). Methods: Six hospitals of Grade III Hospitals that meet the inclusion criteria were selected as research hospitals. ROP screening clinical questionnaires were designed. The birth weight of inpatients at Department of Neonatology, Survey Hospital, from January 1, 2006 to December 31, 2007, was selected. g of premature children as the research object. Results: ① The incidence of ROP was 12.70% in preterm infants with birth weight <2000 g, and the incidence of threshold disease was 3.56%. ② The incidence of ROP in birth weight <1 000 g, 1 000 ~ 1 249 g, 1 250 ~ 1 499 g, 1 500 ~ 1 749 g and 1 750 ~ 2 000 g were 25.00%, 21.80%, 14.20 %, 11.40%, 7.40%. Conclusion: The incidence of ROP in preterm infants with birth weight <2000 g in tertiary hospitals is 12.70%, and the incidence of threshold lesions is 3.56%. As the body weight decreases, the incidence of ROP increases, the more severe the birth weight is an important risk factor for ROP.