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60年代以来,克罗米芬已成为诱导排卵的首选药物,但仍有20%~30%患者对常规应用克罗米芬无反应。为此我们采用克罗米芬延长法诱导排卵26例,共75个周期,结果:排卵有效率,按例为80%(21/26),按周期为65%(49/75);妊娠6例共7次,妊娠率29%(6/21)。认为,此法简单、有效、安全,无一例发生卵巢过度刺激综合征。适用于常规用克罗米芬无效但雌激素水平正常患者。
Since the 1960s, clomiphene has become the first choice of ovulation inducing drugs. However, 20% to 30% of clomiphene do not respond to clomiphene citrate. For this reason, we use clomiphene lengthening method to induce ovulation in 26 cases, a total of 75 cycles, the results: ovulation effective rate of 80% (21/26), according to the cycle was 65% (49/75); 6 cases of pregnancy 7 times, the pregnancy rate was 29% (6/21). That this method is simple, effective, safe, no case of ovarian hyperstimulation syndrome. For routine use of clomiphene citrate but normal estrogen levels in patients.