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硫贲妥钠为临床常用之静脉麻醉药,通过对家兔进行动物试验,我们观察了硫贲妥钠对凝血饥制的影响。方法与结果如下:选取体重在2.5kg 以上的健康家兔两只,心脏采血测定凝血时间,血小板计数,凝血酶元时间,纤维蛋白元定量,血浆鱼精蛋白副凝试验,乙醇胶凝试验等六项验试。然后耳静脉缓慢注入2.5％副硫贲妥钠药液1.3ml/kg 体重。于注药后30分钟、1小时、2小时分别采血,重复测定上述六项试验,结果为下表:(二只平均值):
Thiopental sodium is a commonly used clinical intravenous anesthetic. By animal experiments on rabbits, we observed the effect of thiopental sodium on coagulation. Methods and results are as follows: Two healthy rabbits weighing above 2.5kg were selected, and blood samples were collected for determination of clotting time, platelet count, thrombin time, fibrinogen quantitation, plasma protamine paracoagulation, ethanol gel test, etc. Six tests. Then slow intravenous injection of 2.5% Vice thiophanate sodium solution 1.3ml / kg body weight. 30 minutes after injection, 1 hour, 2 hours were collected blood, repeated testing of the above six tests, the results are as follows: (two average):