急性胰腺炎(acute pancreatitis,AP)是内科的危重急症之一,具有高发病率、高死亡率等特点。据统计,急性胰腺炎患者的死亡率为80%,是继发性感染导致,因此,减少继发性感染的发生,成为降低死亡率的有效途径之一。肠道作为人体最大的细菌库,为继发性感染的发生创造了条件,当肠黏膜 Acute pancreatitis (AP) is one of the critical medical emergencies with high morbidity and mortality. According to statistics, 80% of patients with acute pancreatitis mortality is secondary to infection, therefore, reduce the incidence of secondary infection, as one of the effective ways to reduce mortality. Intestinal tract as the largest bacterial pool, creating conditions for the occurrence of secondary infection, when the intestinal mucosa