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目的探讨缬沙坦联合硝苯地平控释片治疗原发性高血压的临床治疗方法与效果。方法从本院2015年1月至2016年6月期间接收的原发性高血压患者中选取200例,根据治疗方法的不同将其分为观察组与对照组各100例,分别给予缬沙坦结合硝苯地平控释片治疗以及单纯使用硝苯地平控释片治疗,比较两组患者的临床治疗效果以及治疗前后舒张压、收缩压及心率的改善情况。结果经过治疗后,观察组患者显效70例,有效25例,总有效率达到95%,明显高于对照组患者的75%,P<0.05。而对比两组患者治疗前后的舒张压、收缩压以及心率,观察组患者的改善情况也明显好于对照组患者,P<0.05。结论联合缬沙坦与硝苯地平控释片治疗原发性高血压疾病,具有良好应用效果。
Objective To investigate the clinical efficacy and safety of valsartan combined with nifedipine in the treatment of essential hypertension. Methods From January 2015 to June 2016 in our hospital received 200 cases of patients with essential hypertension, according to the different treatment methods were divided into the observation group and the control group of 100 patients were given valsartan The combination of nifedipine controlled release tablets and nifedipine controlled release tablets alone were used to compare the clinical effects and the improvement of diastolic blood pressure, systolic blood pressure and heart rate before and after treatment. Results After treatment, the observation group of patients markedly effective in 70 cases, effective 25 cases, the total effective rate was 95%, significantly higher than 75% of patients in the control group, P <0.05. Comparing the diastolic blood pressure, systolic blood pressure and heart rate before and after treatment in both groups, the improvement in the observation group was also significantly better than that in the control group (P <0.05). Conclusion Combined valsartan and nifedipine controlled release tablets for the treatment of essential hypertension have good effect.