本文研究了人体皮肤上甲酚测定方法。用无水乙醇浸湿的小棉球擦拭一定面积的皮肤上的甲酚，自然挥发干后，用丙酮洗脱，经气相色谱 Ｆ Ｆ Ａ Ｐ 毛细管柱分离， Ｆ Ｉ Ｄ 检测甲酚三种异构体，计算出皮肤上甲酚总量。方法的相对标准偏差小于４ ．６ ％ ；加标回收率在９３ ．２ ％ ～１０４ ％ 之间；检测下限为０ ．１８ｎｇ ，线性范围为０ ．５ ～１０００μｇ／ ｍｌ（２ ．０ ｍｌ 丙酮） 。 This article studies cortisol determination on human skin. Wipe a certain area of ​​cresol on the skin of a certain area with a small cotton ball soaked in absolute ethanol, and then naturally volatilized, eluted with acetone, separated by capillary gas chromatography F F A P column, and detected by F I D Structure, calculate the total amount of cresol on the skin. The relative standard deviation of the method is less than 4. 6%; spiked recoveries at 93. 2% ~ 104%; detection limit is 0. 18ng, the linear range is 0. 5 ~ 1000μg / ml (2.0 ml acetone).