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目的:比较多索茶碱与氨茶碱用于治疗支气管哮喘患者的临床疗效。方法:选取2012年5月—2014年10月间诊治的支气管哮喘患者60例,将其随机分为对照组和治疗组,每组30例;对照组患者均给予氨茶碱治疗,治疗组患者均给予多索茶碱治疗,比较两组患者治疗后症状的缓解率、用力肺活量和肺活量的测得值和不良反应的发生情况。结果:治疗组患者治疗后症状缓解率和不良反应的发生率分别为93.33%和3.33%,优于对照组为70.00%和23.33%(P<0.05);用力肺活量和肺活量测得值高于对照组(P<0.05)。结论:采用多索茶碱治疗支气管哮喘患者的临床疗效优于氨茶碱,可显著改善患者哮喘症状,且不良反应的发生率较低。
Objective: To compare the clinical efficacy of doxofylline and aminophylline in the treatment of patients with bronchial asthma. Methods: Sixty patients with bronchial asthma who were diagnosed and treated between May 2012 and October 2014 were selected and randomly divided into control group and treatment group, 30 cases in each group. Patients in the control group were treated with aminophylline. Patients in the treatment group Were given doxofylline treatment, the two groups of patients after treatment to alleviate the symptoms, forced vital capacity and vital capacity measurements and adverse reactions occurred. Results: The incidences of symptom relief and adverse reactions in the treatment group were 93.33% and 3.33% respectively, which were significantly higher than those in the control group (70.00% vs 23.33%, P <0.05). The values of forced vital capacity and vital capacity were higher than those of the control Group (P <0.05). Conclusion: The clinical efficacy of doxofylline in patients with bronchial asthma is superior to aminophylline, which can significantly improve asthma symptoms and the incidence of adverse reactions is low.