手足口病(Hand,foot and mouth disease,HFMD)是由肠道病毒引起的一种儿童急性传染病,临床以发热和手足口等部位出现皮疹为主要特征,绝大多数病例1周内痊愈,少数病例累及神经、循环和呼吸系统继而发展为重症,重症病例在病程5 d内可出现脑干脑炎、循环衰竭和肺水肿,病死率高。我国自2008年起每年在全国范围均有手足口病的暴发流行,2008-2010年全国报 Hand, foot and mouth disease (HFMD) is a childhood acute infectious disease caused by enteroviruses. It is characterized by fever and rash on the hand, foot and mouth in most cases. Most cases are cured in 1 week, A small number of cases involving the nerves, circulatory and respiratory system and then developed into severe, severe cases of encephalic encephalitis, circulatory failure and pulmonary edema may occur within 5 days of disease duration, high mortality. Since 2008, China has an outbreak of hand-foot-mouth disease in the whole country every year. The National Report 2008-2010