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实验用１６０只Ｗｉｓｔａｒ大鼠自由饮用０．１％氨水８周造成实验性慢性胃炎模型。防治组于诱发胃炎的同时分别用２０％胃康、维霉素水溶液及生理盐水２ｍｌ／只，隔日灌胃８周。治疗组于饮用０．１％氨水８周后，分别用３０％胃康，维霉素水溶液及生理盐水２ｍｌ／只，每日灌胃治疗４周。实验结束后剪尾取血、并进行免疫学检测。结果显示：模型组与正常对照组比较，两批体重增长率均明显减少（Ｐ＜０．０１），体内淋巴细胞转化率和Ｔ细胞酯酶染色阳性率均显著下降（Ｐ＜０．００１），血清凝集素和溶血素、脾脏指数和胸腺指数均无统计学差异（Ｐ＞０．０５）。胃康组体重增长率，淋巴细胞转化率和Ｔ细胞酯酶染色阳性率均较模型组升高（Ｐ＜０．０５），并优于维霉素组。说明胃康在防治实验性慢性胃炎过程中有一定的改善细胞免疫的作用。
Experimental 160 Wistar rats free to drink 0.1% ammonia for 8 weeks to cause experimental chronic gastritis model. Prevention and treatment groups were induced gastritis with 20% of stomach Kang, water and saline, respectively, 2ml / saline every other day for 8 weeks. After treatment with 0.1% aqueous ammonia for 8 weeks, the treatment group was treated with 30% Weikang, aqueous solution of doxorubicin and 2 ml of normal saline respectively for 4 weeks. After the experiment cut tail blood, and immunological testing. The results showed that compared with the normal control group, the weight gain of both groups were significantly decreased (P <0.01), the rate of lymphocyte transformation and the positive rate of T cell esterase were significantly decreased (P <0.001) , Serum lectin and hemolysin, spleen index and thymus index were not statistically different (P> 0.05). Weikang group weight gain rate, lymphocyte transformation rate and T cell esterase staining positive rate than the model group increased (P <0.05), and better than the vitamin group. That Weikang in the prevention and treatment of experimental chronic gastritis have a certain degree of improvement of cellular immunity role.