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目的评价胸痛以及相关临床症状与急性冠脉综合征的关系,识别对急性冠脉综合征有独立预测价值的临床症状。方法对398例临床拟诊为急性冠脉综合征的患者,记录胸痛等临床症状,并行选择性冠状动脉造影明确诊断。采用Logistic多元回归模型分析临床症状与急性冠脉综合征的关系。结果398例中有298例(74.9%)确诊为急性冠脉综合征。急性冠脉综合征组和非冠心病组的年龄、性别和吸烟史差异有显著性(P<0.001),呼吸困难、出汗、恶心或呕吐等临床症状两组差异亦有显著性(P<0.05)。经Logistic多元回归模型分析,出汗、恶心或呕吐是对急性冠脉综合征有显著意义的临床症状(P<0.05)。结论出汗、恶心或呕吐等临床症状是急性冠脉综合征的独立预测症状。
Objective To evaluate the relationship between chest pain and related clinical symptoms and acute coronary syndromes, and to identify the clinical symptoms that have independent predictive value in acute coronary syndromes. Methods A total of 398 patients with clinically suspected acute coronary syndromes were enrolled in this study. Clinical symptoms such as chest pain were recorded and confirmed by selective coronary angiography. Logistic regression model was used to analyze the relationship between clinical symptoms and acute coronary syndrome. Results Of the 398 patients, 298 (74.9%) were diagnosed with acute coronary syndrome. There were significant differences in age, sex and smoking history between acute coronary syndrome group and non-coronary heart disease group (P <0.001). There were also significant differences in clinical symptoms such as dyspnea, sweating, nausea or vomiting between the two groups (P < 0.05). Logistic multivariate regression analysis showed that sweating, nausea or vomiting were significant clinical symptoms of acute coronary syndrome (P <0.05). Conclusions Clinical symptoms such as sweating, nausea or vomiting are independent predictors of acute coronary syndrome.