报告１例特异性皮疹表现为红斑、大疱的Ｂ细胞淋巴瘤。患儿男性，３岁，皮疹表现为全身泛发的红斑以及红斑基础上的大疱，疱壁紧张，疱液清，尼氏征（－）。病程中第一次组织病理检查可见多数表皮下水疱，未见斑块状密集的单一核细胞浸润于皮下及真皮附属器周围。免疫病理检查阴性。２８天后作皮肤和淋巴结组织病理检查及免疫组化证实为ＣＢＣＬ。 One case of a specific rash was reported as an erythematous, bullous B cell lymphoma. Children with children, 3 years old, the rash showed generalized erythema and erythema on the basis of the bullae, blister wall tension, blister fluid clear, Nissl’s sign (-). During the first histopathological examination, most of epidermal blisters were seen. No plaque-like mononuclear cells infiltrated the subcutaneous and dermal appendages. Immunopathological examination negative. Skin and lymph node histopathology and immunohistochemistry were confirmed as CBCL after 28 days.