早期及时地获得再灌流可能中止缺血性脑损伤进一步恶化的进程，以致恢复受累组织的代谢功能［‘］。然而一旦过了一定时限则缺血性损害可能成为不可逆的，此时获得的再灌流可能进一步损伤缺血组织，导致致命的缺血和破坏，最终细胞死亡［’］。再设流损伤是一系列的损伤机制最 Early and timely reperfusion may halt further worsening of ischemic brain injury and restore metabolic function in affected tissues. However, ischemic damage may become irreversible once a certain period of time has passed. The resulting reperfusion may further damage the ischemic tissue, resulting in deadly ischemia and destruction and ultimately cell death. Re-set flow injury is a series of damage mechanism