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目的:探讨65以上老年女性乳腺癌的临床特征和治疗方法。方法:回顾性分析沈阳军区总医院2005年~2012年收治的63例65岁以上老年女性乳腺癌患者的临床资料及治疗效果。结果:全组63例老年乳腺癌占同期收治的乳腺癌患者的15.3%(63/413),38.1%(24/63)的患者合并有其他疾病。74.6%(47/63)的患者以乳房肿块为首发症状。主要病理类型为浸润性导管癌50.8%(32/63)。雌、孕激素受体阳性占69.8%(44/63),C-erbB-2阳性者占30.9%(13/42)。3、5年生存率分别为60.1%、33.2%;中位生存时间为3.9年。结论:老年女性乳腺癌具有其独特的生物学特征,手术、内分泌治疗是主要和有效的治疗方式。
Objective: To investigate the clinical features and treatment of breast cancer in 65 elderly women. Methods: A retrospective analysis of the Shenyang Military Region General Hospital from 2005 to 2012 admitted 63 cases of 65 years of age or older women with breast cancer clinical data and treatment. Results: A total of 63 elderly patients with breast cancer in the same period accounted for 15.3% (63/413) of the patients with breast cancer and 38.1% (24/63) of the patients had other diseases. 74.6% (47/63) of patients with breast lumps as the first symptom. The main pathological type of invasive ductal carcinoma was 50.8% (32/63). The positive rate of estrogen and progesterone receptor was 69.8% (44/63), while the positive rate of C-erbB-2 was 30.9% (13/42). The 3-year and 5-year survival rates were 60.1% and 33.2% respectively. The median survival time was 3.9 years. Conclusion: Breast cancer in elderly women has its own unique biological characteristics. Surgery and endocrine therapy are the main and effective treatments.