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目的:观察益肺饮合支气管动脉灌注化疗治疗老年中晚期非小细胞肺癌的临床疗效、毒副反应及对生活质量的影响。方法:将60例该病患者随机分成治疗组和对照组各30例,对照组采用单纯GP方案支气管动脉灌注化疗,治疗组在对照组化疗基础上加服益肺饮,28d为1个周期,治疗2个周期后比较疗效。结果:两组患者临床症状改善情况、生活质量、毒副反应方面比较,差异均有统计学意义(P<0.05);在瘤体疗效方面比较,两组差异无统计学意义(P>0.05)。结论:益肺饮联合GP方案支气管动脉灌注化疗治疗老年中晚期非小细胞肺癌能够改善患者临床症状、提高生存质量、减轻介入毒副反应。
Objective: To observe the clinical efficacy, side effects and quality of life of Yifeng drinking bronchial arterial infusion chemotherapy in the treatment of middle-late advanced non-small cell lung cancer. Methods: Sixty patients were randomly divided into treatment group (30 cases) and control group (30 cases). The control group received bronchial artery infusion chemotherapy with GP alone. The treatment group was given Fuyifei Yin on the basis of chemotherapy, After 2 cycles of treatment more effective. Results: There were significant differences in clinical symptoms, quality of life and side effects between the two groups (P <0.05). There was no significant difference between the two groups in the therapeutic effect (P> 0.05) . Conclusion: Yifei Yin combined with GP regimen of bronchial arterial infusion chemotherapy in the treatment of advanced non-small cell lung cancer in elderly patients can improve clinical symptoms, improve quality of life and reduce the toxic effects of intervention.