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目的探讨近30年来糖尿病肾病中医药/中西医结合临床治疗中医药研究的趋向及特点,为此后的中医药/中西医结合治疗糖尿病肾病提供借鉴。方法遵循循证医学评价文献的原则,以维普咨询中文科技期刊数据库(1989-2009)、中国期刊全文数据库(CNKI)(1979-2009)、万方数据库(1982-2009)、中国生物医学文献数据库(CBM)(1990-2009)、中文生物医学期刊数据库(CMCC/CMCI)(1994-2009)为资料源,全面检索1984—2009年间的糖尿病肾病治疗类文献,使用Epidta双录入数据,全部数据导出至SPSS13.0,从研究现状、特点及发展走向几个方面进行计量学评价分析。结果共检索出文献2300篇,其中涉及临床经验或个案类文章196篇、病因病机研究类53篇、辨证治疗类58篇、各中医治法治疗类117篇、自拟方及成方治疗类613篇、中成药和单味中药治疗类563篇、中药联合ACEI/ARB研究类700篇,不同类型文献起始、兴盛年份各不相同。结论临床经验或个案研究、辨证治疗研究起步较早,近年来RCT研究成为热点,不过目前RCT文献质量仍需进一步提高,设计科学、方法严谨、大样本、多中心的糖尿病肾病中西医结合RCT研究为今后重要发展方向。
Objective To explore the trends and characteristics of traditional Chinese medicine / traditional Chinese medicine combined with western medicine in the past 30 years for the treatment of diabetic nephropathy with traditional Chinese medicine and western medicine. Methods According to the principles of evidence-based medical evaluation literature, the Chinese Journal of Science and Technology Periodical Database (1989-2009), Chinese Journal Full-text Database (1979-2009), Wanfang Database (1982-2009), Chinese Biomedical Literature Database (CBM) (1990-2009), Chinese Journal of Biomedical Journals (CMCC / CMCI) (1994-2009) as the data source, a comprehensive search of the literature on the treatment of diabetic nephropathy between 1984 and 2009 was conducted. All data were derived using Epidata double entry data To SPSS13.0, from the research status, characteristics and development direction of several aspects of econometric evaluation. Results A total of 2,300 literatures were retrieved, of which 196 were involved in clinical experience or individual case articles, 53 were etiological and pathogenetic studies, 58 were syndrome differentiation and treatment, 117 were TCM treatment and treatment, 613 articles, 563 articles of traditional Chinese medicine and single Chinese medicine, and 700 articles of Chinese traditional medicine combined with ACEI / ARB. The literatures of the different types originated and prospered were different from each other. Conclusions Clinical experience or case study and dialectical treatment study started earlier. In recent years, RCT research has become a hot spot. However, the quality of RCT literature still needs to be further improved at present. Scientific and rigorous methods, large sample and multicenter diabetic nephropathy For future important direction of development.