骨髓移植在国内尚是一个较新课题,关于骨髓移植后出现移植物抗宿主病(GVHD)的病理改变,国内未见报告,文介绍部分HLA配型相合进行同种异体骨髓移植存活32天后死亡的尸检所见,并对其临床病理特点与发生原因作初步探讨。 临床资料 患者辛××,男性、19岁、社员,住院号180809,以鼻衄20多天于1980年10月29日入院,病人病前二个月因腹泻曾服氯霉素6片,入院前20多天无诱因鼻衄不止,流血1000毫升,经鼻腔填塞而止,曾输血600毫升,自觉头晕、心悸、皮肤紫点,因鼻衄反复不止而入院, Bone marrow transplantation in China is still a relatively new topic, on bone marrow transplantation occurred after graft-versus-host disease (GVHD) pathological changes, no domestic report, the article describes the part of HLA matching allograft bone marrow transplantation survival after 32 days of death Of the autopsy seen, and its clinical and pathological features and causes for a preliminary discussion. Clinical data Patients Xin × ×, male, 19 years old, members, hospital number 180,809, more than 20 days to epistaxis in October 29, 1980 admission, patients with diarrhea two months before taking chloramphenicol 6 tablets, admission No more than 20 days before the epistaxis Epistaxis, bleeding 1000 ml, filling the nose through the stop, had transfused 600 ml, consciously dizzy, palpitations, skin purple point, due to epistaxis repeatedly admitted more than,