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相当部分的急淋病例现在被认为是可治愈的。本文讨论如何提高诱导缓解的问题。 20例急淋在首次诊断后,联合使用强的松、长春新碱和左旋天门冬酰胺酶:强的松每天40毫克/平方米共4周,长春新碱每周1.5毫克/平方米共4周,左旋天门冬酰胺酶400单位/公斤,每周2次,共2～4周,随骨髓象是早期或晚期达到正常标准而定。本组男8例,女12例,年龄2～22岁(17例小于15岁)。6例大原淋巴细胞型、3例小原淋巴细胞型、1例原幼淋巴细胞型和/或分类不明型,10例幼淋巴细胞型。所有病人均按以上方案治疗,其中19例在2周后,1例在4周后全部得到缓解,未见严重毒性反应。作者
A significant portion of acute cases are now considered curable. This article discusses how to improve the induction of remission. 20 cases of acute leaching after the first diagnosis, the combination of prednisone, vincristine and levo-asparaginase: prednisone 40 mg / m2 for 4 weeks, vincristine 1.5 mg / m2 for a total of 4 Week, L-asparaginase 400 units / kg, 2 times a week for a total of 2 to 4 weeks, with the bone marrow as early or late to normal standards may be. The group of 8 males and 12 females, aged 2 to 22 years (17 cases less than 15 years old). 6 cases of large lymphocytic, 3 cases of small lymphocytic, 1 cases of primitive lymphocytic and / or unknown classification, 10 cases of lymphocytic. All patients were treated according to the above protocol, of which 19 cases were relieved after 2 weeks and 1 case after 4 weeks, and no serious toxic reaction was found. Author