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利用相转移催化法制备了磷胺霉素全合成的关键中间体——3-(N-对甲苯磺酰-N-苄氧基氨基)-1-氯丙烷(2)(X=Cl),收率可达90%。
The key intermediates for the complete synthesis of fosamycins were prepared by phase-transfer catalysis, which is 3-N-tosyl-N-benzyloxyamino-1-chloropropane Yield up to 90%.