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目的：研究急性白血病（ＡＬ）细胞抗原表达特征及临床意义。方法：选用１４～１６ 种单克隆抗体，采用免疫荧光的方法，对９６例ＡＬ患者进行免疫分型。结果：９ 例为多系表达，即同时表达三系以上的抗原（急性髓细胞白血病－ＡＭＬ７ 例，急性淋巴细胞白血病－ＡＬＬ２ 例），ＡＭＬ中多系表达发生率为１０．８％ ，ＡＬＬ中为６．５％ 。“裸细胞”型的发生率ＡＭＬ中７．７％ ，ＡＬＬ中６．４％ 。结论：呈多系表达的ＡＭＬ多为Ｍ５ 型，ＣＤ１４高表达，Ｐ－１７０ 高表达，ＣＲ率低；ＡＬＬ则发生于复发的病人
Objective: To study the expression characteristics and clinical significance of acute leukemia (AL) cell antigens. Methods: Fourteen to sixteen monoclonal antibodies were used to immunophenotype 96 AL patients by immunofluorescence. RESULTS: Nine cases were multi-lineage expression, ie more than three lines of antigens were simultaneously expressed (7 cases of acute myeloid leukemia-AML, and ALL cases of acute lymphoblastic leukemia), and the multilineage expression rate in AML was 10.8%. It is 6.5%. The incidence of “naked cell” type was 7.7% in AML and 6.4% in ALL. CONCLUSIONS: Most of the multilineage AMLs are M5 type, high expression of CD14, high expression of P-170, low CR rate; ALL occurs in relapsed patients