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我们用国产胺苯吖啶(AMSA)为联合化疗方案治疗急性白血病(AL)28例,并进行了临床观察,取得了较为满意的效果。现报道如下。 1 病例与方法 1.1 病例选择 28例急性白血病,女性10例,男性18例,年龄在21岁～57岁,平均年龄33岁。急性淋巴细胞白血病(ALL)12例(初发6例,复治或复发6例),急性非淋巴细胞白血病(ANLL)13例(初发9例,复治复发4例),AL获完全缓解(CR)者强化治疗3例。全部病例均进行骨髓细胞形态学及细胞化学检查,部分患者作免疫表型分析。均符合我国急性白血病的诊断标准。
We used domestic AMAZ for the treatment of acute leukemia (AL) in 28 cases. Clinical observations were performed and satisfactory results were obtained. The report is as follows. 1 cases and methods 1.1 Case selection 28 cases of acute leukemia, 10 females, 18 males, aged 21 to 57 years, mean age 33 years. Acute lymphoblastic leukemia (ALL) in 12 cases (6 cases of primary recurrence, retreatment or recurrence in 6 cases), acute non-lymphocytic leukemia (ANLL) in 13 cases (9 cases of initial recurrence, recurrence of recurrence in 4 cases), AL complete remission (CR) intensive treatment in 3 cases. Bone marrow cell morphology and cytochemistry were performed in all cases, and some patients were analyzed for immunophenotype. All meet the diagnostic criteria of acute leukemia in China.