药物在不同的时间内使用,其产生的效果和反应也不尽相同。 生物节律研究显示,早上起床后的2小时内,人体释放出较高水平的肾上腺素和去甲肾上腺素,促使心跳加快,血管收缩,血压升高,加上此时的血小板聚集功能最活跃,可导致血柱形成,血管阻塞和心肌缺血,坏死,而诱发心肌梗塞或心性猝死。 最近,德国心脏病专家旺·门敦教授指出,冠心病病人的药物治疗应根据人体生物节律来安排。目前治疗冠心病最常用的三类药物,即硝酸盐类、β—受体阻滞剂、钙通道拮抗剂的作用都受人体生物节律的明显影响。 研究显示,硝酸盐类药物三硝酸酯在上午服用能使冠状动脉扩张,而下午服用即使同样药量,对冠状 Drugs used at different times, the effect and response are not the same. Biorhythm studies have shown that within 2 hours after getting up in the morning, the body releases higher levels of epinephrine and norepinephrine, which leads to faster heartbeat, vasoconstriction and higher blood pressure, and the platelet aggregation function is the most active at this time. Can lead to blood column formation, vascular occlusion and myocardial ischemia and necrosis, and induce myocardial infarction or sudden cardiac death. Recently, Professor Wang Menten, a German cardiologist, pointed out that medical treatment of patients with coronary heart disease should be arranged according to the biological rhythm of the human body. At present, the three most commonly used drugs for treating coronary heart disease, namely nitrates, β-blockers and calcium channel antagonists, are all significantly affected by the biorhythm of the human body. Studies have shown that nitrate nitrate trinitrate in the morning to make coronary dilatation, and even taking the same afternoon dose, the coronas