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目的：观察中西医结合治疗活动性狼疮性肾炎的疗效。方法：将３１９例活动性狼疮性肾炎分为西医组和中西医结合治疗组。西医组用激素标准疗程、环磷酰胺冲击治疗；中西医结合组在西医治疗的基础上辨证加用中药，观察临床有效率和副反应。结果：中西医结合治疗组有效率为 ８５， ３％，西医组为 ７３． ７ ％；中西组副反应发生率为３６．１％，西医组为７３．１％，Ｐ＜０．０５；中西组感染率及死亡率分别为２３．３ ％、８．０％，西医组为５３．２％和１６．７％，Ｐ值分别为小于０．０１和小于０．０５。中西组复发率为８．０％，西医组为２３．７％，Ｐ＜０．０５。结论：中西医结合治疗活动性狼疮性肾炎可以降低西药副作用发生率，减少感染并发症发生率，降低复发率和病死率。
Objective: To observe the curative effect of integrated traditional Chinese and western medicine on active lupus nephritis. Methods: 319 cases of active lupus nephritis were divided into western medicine group and integrated traditional Chinese and western medicine treatment group. Western medicine treatment group with hormone standard, cyclophosphamide impact treatment; Integrative Medicine Group on the basis of Western medical treatment plus traditional Chinese medicine syndrome differentiation, observation of clinical efficacy and side effects. Results: The effective rate of the combination of traditional Chinese and western medicine was 85% and 3% respectively, and that of the western medicine group was 73%. The incidence of side effects in Chinese and Western patients was 36.1% and in Western doctors was 73.1% (P <0.05). The infection rates and death rates in Chinese and Western patients were 23.3% and 8.0% Was 53.2% and 16.7% respectively, P values were less than 0.01 and less than 0.05, respectively. Western recurrence rate was 8.0%, Western medicine group was 23.7%, P <0.05. Conclusion: Integrative treatment of active lupus nephritis can reduce the incidence of Western side effects, reduce the incidence of infection complications, reduce the recurrence rate and mortality.