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目的:探讨乙二胺四乙酸盐(EDTA)依赖性血小板假性减少症的发生与获得性自身免疫病的关系。方法:采用血细胞分析仪测定恶性肿瘤患者化疗前后血小板数量,与手工计数法测得的血小板数量相比较;确定恶性肿瘤患者化疗前后EDTA依赖性血小板假性减少症的发生率。结果:经化学治疗后的恶性肿瘤患者EDTA依赖性血小板假性减少症的发生率较化疗前明显增高。结论:EDTA依赖性血小板假性减少症与获得性自身免疫病相关联。
Objective: To investigate the relationship between the occurrence of pseudo-edema in EDTA-dependent platelets and acquired autoimmune diseases. Methods: The number of platelets in patients with malignant tumor before and after chemotherapy was determined by hematology analyzer, compared with the number of platelets measured by manual counting method. The incidence of EDTA-dependent pseudo-platelet hypothyroidism in patients with malignant tumor before and after chemotherapy was determined. Results: The incidence of EDTA-dependent pseudo-thrombocytopenia in patients with malignant tumors after chemotherapy was significantly higher than that before chemotherapy. Conclusion: EDTA-dependent thrombocytopenia is associated with acquired autoimmune disease.