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目的探讨前列舒通和盐酸坦索罗辛缓释胶囊(哈乐)联合治疗前列腺增生的临床效果。方法 96例良性前列腺增生患者,随机分为实验组和对照组,各48例。实验组给予前列舒通胶囊联合哈乐治疗,对照组仅给予哈乐治疗。比较两组疗效。结果实验组总有效率为93.75%,高于对照组的79.17%(P<0.05)。治疗后,两组国际前列腺症状评分表(IPSS)评分、最大尿流率(Qmax)、膀胱剩余尿量(PVR)、前列腺体积均较治疗前改善,实验组改善程度优于对照组(P<0.05)。实验组躯体功能、角色功能、认知功能、情绪功能评分改善程度优于对照组(P<0.05)。结论前列舒通加哈乐治疗前列腺增生临床效果显著,在改善患者临床症状、前列腺功能以及生存质量上有明显临床优势,可作为优选治疗方案。
Objective To investigate the clinical effect of Qianlieshutong and tamsulosin hydrochloride sustained release capsules (Harmony) in the treatment of benign prostatic hyperplasia. Methods 96 cases of benign prostatic hyperplasia patients were randomly divided into experimental group and control group, 48 cases each. The experimental group was given Qianlieshutong capsule combined with Hara treatment, the control group was given Hara treatment. Compare the two groups curative effect. Results The total effective rate in the experimental group was 93.75%, which was higher than 79.17% in the control group (P <0.05). After treatment, the scores of IPSS, Qmax, PVR and prostate volume in both groups were better than those before treatment, and the improvements in the experimental group were better than those in the control group (P < 0.05). The improvement of physical function, role function, cognitive function and emotional function score of experimental group was better than that of control group (P <0.05). Conclusions Qianlieshutongjialele has significant clinical effect in treating benign prostatic hyperplasia, and has obvious clinical advantages in improving clinical symptoms, prostate function and quality of life, and can be used as the preferred treatment plan.