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NK细胞在肌体内担当对病毒与肿瘤的免疫防御的重要任务。近年来,这些疾病用干扰素(IFN)进行治疗,其所以有效果与NK细胞的活性有密切关系。已有的报导中提出,成人末梢血中NK细胞的单克隆抗体有Leu-4~+,Leu-7~+,Leu-11~+等。在大部份淋巴组织中存在有Leu-4~+,Leu-7~+,Leu-11~-。在形态上有Azur颗粒、ACP阳性的淋巴细胞。作者在明确了颗粒淋巴细胞(GL)与Leu-7~+细胞,Leu-11~+细胞间的关连后,研究了各种疾病发生时是否会出现GL的增减,亦即NK细胞增减的
NK cells play an important role in the body’s immune defense against viruses and tumors. In recent years, these diseases are treated with interferon (IFN), so the effect is closely related to the activity of NK cells. It has been reported in reports that monoclonal antibodies to NK cells in adult peripheral blood have Leu-4 ~ +, Leu-7 ~ +, Leu-11 ~ + and the like. Leu-4 ~ +, Leu-7 ~ +, Leu-11 ~ - are found in most of the lymphoid tissues. Azur particles in morphology, ACP-positive lymphocytes. After clarifying the association between granulosa lymphocytes (GL) and Leu-7 ~ + cells and Leu-11 ~ + cells, we investigated whether GL increased or decreased at various disease events, ie, increased or decreased NK cells of