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目的:探讨盐酸舍曲林片对抑郁的稳定期慢性阻塞性肺疾病患者的影响。方法:将120例抑郁的稳定期慢性阻塞性肺疾病患者随机分为常规组和实验组,常规组仅实施常规的治疗,实验组除给予常规的治疗,还给予盐酸舍曲林片口服,抗抑郁治疗,5周后评价患者的肺功能及抑郁状态。结果:实验组和常规组比较,患者肺功能指标改善,HAMD评分亦显著低于常规组(P<0.05)。结论:盐酸舍曲林片能改善慢性阻塞性肺疾病患者的肺功能及抑郁情绪。
Objective: To investigate the effect of sertraline hydrochloride tablets on patients with chronic obstructive pulmonary disease in stable phase. Methods: A total of 120 patients with stable chronic obstructive pulmonary disease (COPD) were divided into routine group and experimental group randomly. Conventional treatment was given only in the conventional group. In addition to routine treatment, the experimental group was given sertraline hydrochloride tablets orally, Depression treatment, 5 weeks after the evaluation of patients with lung function and depression. Results: Compared with the conventional group, the lung function index and the HAMD score of the experimental group were significantly lower than those of the conventional group (P <0.05). Conclusion: Sertraline hydrochloride can improve pulmonary function and depression in patients with chronic obstructive pulmonary disease.