HIF-1α在子宫内膜腺癌中的表达与意义

来源 :泸州医学院学报 | 被引量 : 0次 | 上传用户:ryan_cheng
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的:通过检测缺氧诱导因子-1α(HIF—1α)在子宫内膜腺癌中的表达,探讨它在子宫内膜腺癌发生发展机制中的作用。方法:采用免疫组织化学SP法,分别检测14例正常子宫内膜组织、15例子宫内膜不典型增生组织及56例子宫内膜腺癌组织中HIF-1α 的表达。结果:HIF-1α 在子宫内膜腺癌组织、子宫内膜不典型增生组织、正常子宫内膜组织中的阳性表达率分别为92.86%、53.33%和7.14%,其表达差异有统计学意义(x^2=40.483,P=0.000)。子宫内膜腺癌组织中HIF-1α 的阳性表达率与正常子宫
其他文献
目的:对重组流行性乙型脑炎病毒E基因0EVE)进行优化表达研究。方法:采用正交实验设计L9(34)方案,通过SDS—PAGE分析,对诱导时机、诱导时间、IPTG浓度、诱导温度四因素对重组产物表达
目的:探讨大肠癌组织中Survivin及其剪接变异体Survivin—△Ex3、Survi—vin-2BmRNA在大肠癌组织的表达规律。方法:采用逆转录-聚合酶链反应(RT—PCR)检测50例(高分化20例,中低分化
Between August 1976 and May 1988,43 patients had their heart valve prostheses replaced.The total mortality was as high as 25.6%,but the operative mortality was
Objective. To investigate the differentiation process of the human glioblastoma cells. Methods. Differential display reverse transcribed-PCR(DDRT-PCR) was used
陕西省政协委员,宝鸡市政协常委,陕西宝鸡专用汽车有限公司董事长王宝和连续八年为宝鸡市市委、市人大、市政府、市政协领导,宝鸡市全体政协委员赠阅《各界》杂志。值此人民政协
高校志愿服务活动开展,应重点做好组织架构构建、志愿服务团队组建、服务项目研发、规范管理四个方面的工作,规范志愿服务流程,提升服务质量.
The expression ot mRNA for bone morphogenetie protein-l(BMP-1) was investigated in fetal human cartilage and bone during the developing endoehondral ossificatio
This study focused on the influences of opioids on the generation of antibody againse sheep erythrocyte in vitro.It was found that morphine,a-CAO,DADLE,MENK wer
Effects of genistein on invasion and matrix metalloproteinase activities were investigated in HT1080 human sarcoma cells, lnvasion of HTI080 cells through recon
The effect of intrathecal injection of dynorphin A(1-17) on second messenger systems of spinal cord relative to behavioral change in rats was studied. Dynorphin