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随着不育不孕治疗手段的盛行,世界各地的多胎妊娠率显著提高。与正常妊娠相比,经辅助生殖技术治疗后单卵双胎发生率显著增加。单卵双胎因伴随高风险的并发症而备受关注。然而,单卵双胎发生的相关因素及其发生机制仍未明确。本文概述了单卵双胎的概念、类型、并发症、辅助生殖技术中影响单卵双胎发生的相关因素及发生机制假说,并提出了单卵双胎研究过程中急需解决的一些问题。
With the prevalence of treatment of infertility infertility, multiple pregnancy rates around the world increased significantly. Compared with normal pregnancy, the incidence of monozygotic twins increased significantly after assisted reproductive technology. Monozygotic twins are of concern because of the high risk of complications. However, the related factors and their mechanisms of monozygotic twins are still not clear. This article summarizes the concepts, types and complications of monozygotic twins, the related factors affecting the occurrence of monozygotic twins and the mechanism hypothesis in assisted reproductive technology, and puts forward some problems which are urgently needed to be solved in the study of monozygotic twins.