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目的 :观察甘露醇治疗短暂性脑缺血 (transientischmicattackTIA)的疗效。方法 :用甘露醇治疗TIA90例 ,用传统维脑路通静滴作为对照组治疗 87例 ,比较两组入院前 1 0d ,入院后治疗前 1 0d和后1 0d发作 ,次数。结果 :甘露醇组入院前 1 0dTIA发作次数 1 2 .4± 6 .8,入院后治疗前 1 0d为 5 .2± 2 .2 ,治疗后 1 0d为 3 .0± 0 .1 ,对照组入院前 1 0d为 1 1 .8± 4.8,入院后治疗前 1 0d为 7.8± 3 .2 ,治疗后 1 0d为 6 .5±1 .5 ,治疗前 1 0d时甘露醇组明显优于对照组 (P <0 .0 1 ) ,治疗后 1 0d时也明显优于对照组 (P <0 .0 1 )。结论 :甘露醇抗自由基治疗较传统的基础药物治疗后 ,TIA发作次数减少明显
Objective: To observe the efficacy of mannitol in the treatment of transient ischemic attack (transientischmicattack TIA). Methods: Ninety patients with TIA were treated with mannitol. Eighty-seven patients were treated with intravenous infusion of Venoruton as the control group. The incidences of the attacks and the number of attacks were compared between the two groups before admission and at 10 days and 10 days after admission. Results: Mannitol group before admission 10dTIA episodes of 12.4 ± 6. 8, 10d before admission after treatment was 5.2 ± 2.2, 10d after treatment was 3.0 ± 0. 1, the control group Before admission, the odds ratio was 118.8% before admission, 7.8 ± 3.2 days before admission, 10.5 days after treatment, and was significantly higher than the control at 10 days before treatment Group (P <0.01), also significantly better than the control group (P <0.01) at 10 days after treatment. Conclusion: Mannitol anti-free radical therapy significantly reduced the number of TIA episodes after treatment with traditional medicines