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目的探讨一种安全、有效、费用低、不良反应相对较少的终止早孕的镇痛方法。方法自愿参加该项工作,无相关禁忌证且孕周<10周的要求行人工流产的早孕妇女120例,随机分为3组,每组各40例。Ⅰ组:术前3小时阴道后穹隆上米索前列醇400μg,施行手术前30分钟肌注盐酸山莨菪碱5mg,施行手术时1%盐酸利多卡因宫颈注射;Ⅱ组:宫颈注射1%盐酸利多卡因;Ⅲ组:即对照组,不进行任何干预。结果镇痛效果:Ⅰ组最佳,与Ⅱ、Ⅲ组比较差异显著。Ⅱ组效果次之,与Ⅲ组比较差异仍明显。宫颈松弛情况Ⅰ组效果最佳,Ⅱ组次之,Ⅲ组最差,3组间比较差异有显著性。人工流产综合征(RAAS)发生率Ⅰ组发生率最低,仅1例,Ⅱ组2例,Ⅲ组8例。结论Ⅰ组具有安全有效、操作简便、价格低廉的特点,是一种较好的能够广泛应用的镇痛方法。
Objective To explore a safe, effective, low cost, adverse reaction is relatively less termination of early pregnancy analgesia. Methods Volunteer to participate in this work, without contraindications and gestational weeks <10 weeks require abortion of early pregnant women, 120 cases were randomly divided into 3 groups, 40 cases in each group. Group Ⅰ: 400μg of misoprostol on vaginal posterior fornix 3 hours before operation, and 5mg of anisodamine hydrochloride intramuscularly 30% before operation, and 1% of lidocaine hydrochloride was injected into cervix during operation. Group Ⅱ: Cervical injection of 1% hydrochloric acid Lidocaine; group Ⅲ: the control group, without any intervention. Results The analgesic effect was the best in group Ⅰ, but significantly different from that in group Ⅱ and Ⅲ. The effect of group Ⅱ was second, and the difference was still obvious compared with group Ⅲ. Cervical relaxation in the best effect in group Ⅰ, Ⅱ followed, the third group was the worst, the difference between the three groups was significant. The incidence of induced abortion syndrome (RAAS) was the lowest in group Ⅰ, only 1 case, 2 cases in group Ⅱ and 8 cases in group Ⅲ. Conclusion Group Ⅰ is safe and effective, easy to operate, inexpensive and is a good analgesic method that can be widely used.