肿瘤微转移是引起肿瘤复发和转移的主要原因,也是分子诊断分期的重要依据。肺癌微转移的研究范围包括淋巴结微转移、骨髓微转移、外周血微转移及胸膜腔微转移。检测非小细胞肺癌微转移,对非小细胞肺癌患者的准确分期、治疗方案的选择、手术方案的确定、化疗效果的及时评估和预后预测都起着非常重要的作用。 Tumor micrometastasis is the main cause of tumor recurrence and metastasis, but also an important basis for molecular diagnosis staging. The study of micrometastasis in lung cancer includes micrometastasis of lymph nodes, micrometastasis of bone marrow, micrometastasis of peripheral blood and micrometastasis of the pleural cavity. Detection of micrometastases in non-small cell lung cancer plays a very important role in the accurate staging of patients with NSCLC, the choice of treatment options, the determination of the operative protocol, the timely assessment of the chemotherapeutic effect, and the prediction of prognosis.