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目的观察联合应用普米克令舒、γ-干扰素对毛细支气管炎后喘息发作的阻碍作用。方法将168例2003年9月至2005年10月在宁波大学医学院附属医院儿科住院的毛细支气管炎患儿按入院顺序分成四个组即:普米克令舒组、γ-干扰素组、联合运用普米克令舒和γ-干扰素组和对照组,观察一年内再次发生喘息的例数。结果γ-干扰素组一年内再发喘息数为14例,普米克令舒组为13例,联合组为4例,对照组为22例。结论联合应用γ-干扰素、普米克令舒较单独应用普米克令舒对再次喘息的阻碍作用更佳。
Objective To observe the inhibitory effect of combination of pulmicort and interferon-gamma on wheezing after bronchiolitis. Methods From January 2003 to October 2005, 168 children with bronchiolitis who were hospitalized in pediatrics of Affiliated Hospital of Ningbo University Medical College were divided into four groups according to hospital admission sequence: Pulmicort group, γ-interferon group, Pulmicort and interferon-γ groups and control groups were used to observe the number of wheezing episodes within a year. Results In the interferon-γ group, 14 cases were relapsed in one year, 13 cases in the pulmicort group, 4 cases in the combined group and 22 cases in the control group. Conclusions Combination of interferon-γ and pulmicort suppressive effect on respite wheeze better than pulmicort alone.