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作者报道氟哌酸与肌注壮观霉素治疗淋病(PPNG和非PPNG株)的疗效对比试验。547例淋病患者,随机接受单剂氟哌酸(800mg,口服)或壮观霉素(2g,肌注)。病人恢复4～8天后,分析其疗效、安全性。随访482例,氟哌酸治疗者(94例为PPNG菌株,145例为非PPNG菌株)及壮观霉素治疗的82例PPNG感染者,均治愈。壮观霉素治疗的161例非PPNG菌株感染者,159例(99％)治愈。副作用:氟哌酸治疗者3例出现头痛、恶心和失眠。壮观霉素治疗
The authors report the efficacy of norfloxacin compared with intramuscular injection of spectinomycin for the treatment of gonorrhea (PPNG and non-PPNG strains). 547 gonorrhea patients were randomized to receive either a single dose of norfloxacin (800 mg orally) or spectinomycin (2 g intramuscularly). The patient recovered 4 to 8 days after the analysis of its efficacy and safety. 482 follow-up, norfloxacin treatment (94 cases of PPNG strains, 145 cases of non-PPNG strains) and spectinomycin treatment of 82 cases of PPNG infection were cured. 161 cases of spectinomycin-treated non-PPNG strains were infected, 159 cases (99%) cured. Side effects: 3 cases of norfloxacin treatment of headache, nausea and insomnia. Spectinomycin treatment