目的　采用 3种方法控制恶性肿瘤联合化疗所致急性恶心、呕吐。方法　常规用药组(Ⅰ )、枢复宁组 (Ⅱ )、针药并用组 (Ⅲ )对 391例国人不同类型恶性肿瘤进行临床观察 ,结果　Ⅱ、Ⅲ组疗效明显高于Ⅰ组 (P <0 0 5)、Ⅱ、Ⅲ组疗效相当 ,控制恶心效果 ,虽然最初 2 4小时以Ⅱ组为高(84 % )、Ⅲ组 71% ,但整个疗程 ,效果相当 ,且Ⅲ组对肝疾患者效果优于Ⅱ组 ,弥补了枢复宁的不足。结论　针药并用组 ,疗效显著 ,且中药药源广泛 ,价格低廉 ,针刺简便易行 ,是值得推广的一种方法。 Objective To use three methods to control acute nausea and vomiting caused by malignant tumor combined with chemotherapy. Methods The clinical observations of 391 cases of different types of malignant tumors were made in the conventional drug group (I), the Shufuning group (II) and the acupuncture and medicine group (III). The results were significantly higher in group II and III than in group I (P < 0 0 5), II, III groups have similar efficacy and control of nausea. Although the first 24 hours were in group II (84%) and group III (71%), the effect was comparable throughout the course of treatment, and group III was effective in patients with liver disease. Better than the group II, to make up for the lack of Shu Fu Ning. Conclusion The combined use of acupuncture and medicine has remarkable curative effect, and the sources of traditional Chinese medicine are extensive, the price is low, and acupuncture is simple and easy to carry out. It is a method worthy of promotion.