目的 研究临床护理干预在老年慢性阻塞性肺疾病（COPD）护理工作中的应用效果及对患者生存质量的影响。方法 入组对象为我院2018年7月至2019年7月收治的180例老年COPD患者，随机分为两组，对比组（90例）患者实施常规护理，主要包括为患者做好入院接待和指导，并对患者进行健康知识宣教。为患者进行血压、心率等的检查，并对用药事项和饮食禁忌进行告知。探讨组（90例）患者实施临床护理干预，主要包括心理护理、生活习惯和饮食习惯干预、环境护理以及运动锻炼护理等，对比两组患者的肺功能指标、生活质量以及负性情绪。 “,”Objective To study the application effect of clinical nursing intervention in elderly patients with chronic obstructive pulmonary disease (COPD) and the effect on patients\' quality of life. Methods The 180 elderly patients with COPD admitted to our hospital from July 2018 to July 2019 were randomly divided into two groups. The control group (90 cases) received routine care， mainly including admission reception and guidance for patients， and health education for patients. Blood pressure and heart rate were checked for the patients， and medication matters and dietary contraindications were informed. The study group (90 cases) received clinical nursing intervention， mainly including psychological nursing，living habits and eating habits intervention， environmental nursing and exercise nursing， etc， and compared the lung function indicators， quality of life and negative emotions of patients in the two groups. Results FEV1 and FEV1/FVC in the two groups were significantly improved after nursingcompared with before nursing (P＜0.05). The detection values of FEV1 and FEV1/FVC in the discussion group were higher than those in the control group (P＜0.05). The four scores of quality of life in the study group were significantly higher than that in the control group (P＜0.05). After nursing， the SAS score and SDS score of the two groups were compared， the discussion group was lower (P＜0.05). Conclusion Clinical nursing intervention， through targeted psychological nursing， diet and lifestyle intervention as well as exercise guidance and other nursing methods， hospital intervention for patients， greatly improve the patient compliance， significantly improve lung function， alleviate.