人类新基因UHRF1生物学功能的研究进展

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hUHRF1是最近发现的一个新基因,与鼠UHRF1基因同属UHRF家族.目前,有关鼠mUHRF1基因的功能研究较多,且多以胚胎干细胞为研究对象;hUHRF1基因编码的蛋白序列与鼠mUHRF1之间有73.7%的同源性,那么,hUHRF1基因是否也具有类似鼠mUHRF1基因的功能?该基因在体细胞中的功能又如何?因此,有关hUHRF1基因功能的研究成为必然,现就相关的内容综述如下.
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