英《医学新闻周刊》第13卷第5期(1981年)报道:最近在人尿中发现一种物质,与已知的一种抗有丝分裂的植物成分极为相似,对人具有周期性活性,可能作为一种抗癌药。这种尿内的物质名为HPMF,属于内酯化学族,以前只在植物中存在,其特性之一是抑制细胞分裂。例如鬼臼毒素从美国野生盾叶鬼臼中取得,传统上是用作通便剂,但具有一些抗有丝分 The British Medical News Weekly, Vol. 13, No. 5 (1981) reported that a substance recently discovered in human urine is very similar to a known anti-mitotic plant component and is cyclically active in humans. As an anticancer drug. This urinary substance is called HPMF and belongs to the lactone chemical family. It used to exist only in plants. One of its characteristics is to inhibit cell division. For example, podophyllotoxin is obtained from the American wild shield leafhopper, which is traditionally used as a laxative but has some anti-filamentary properties.