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目的探讨雾化吸入方式治疗婴幼儿哮喘的临床疗效。方法选取隆林各族自治县人民医院儿科2013年9月—2014年8月收治的哮喘患儿90例,按照入院先后顺序将其分为试验组(n=45)与对照组(n=45),试验组患儿的雾化吸入治疗采取氧气射流雾化法,给予盐酸氨溴索粉针与硫酸沙丁胺醇溶液进行交替雾化吸入治疗,对照组患儿给予静脉滴注甲强龙和氨茶碱常规治疗。比较两组患儿临床疗效、咳嗽消失时间、喘憋消失时间、哮鸣音消失时间、住院时间及不良反应发生率。结果试验组总有效率高于对照组,咳嗽消失时间、喘憋消失时间、哮鸣音消失时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。两组患儿治疗期间,均未出现严重的不良反应。结论雾化吸入方式治疗婴幼儿哮喘的临床疗效确切,可明显缩短患儿症状消失时间及住院时间,具有使用剂量小、安全性高等优势。
Objective To investigate the clinical effect of inhalation on asthma in infants and young children. Methods Ninety children with asthma admitted from September 2013 to August 2014 in People’s Hospital of Longlin Autonomous County People’s Hospital were divided into experimental group (n = 45) and control group (n = 45) , The experimental group of children with inhalation therapy using oxygen jet atomization method to give ambroxol powder needle and salbutamol sulfate solution alternately inhalation therapy, control children with intravenous infusion of methylprednisolone and aminophylline Conventional treatment. The clinical efficacy, cough disappear time, wheezing disappear time, wheeze disappearance time, hospital stay and incidence of adverse reactions were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the control group. The disappearance of cough, the disappearance of wheezing, the disappearance of wheeze, and the length of hospital stay were all shorter than those of the control group (P <0.05). Two groups of children during treatment, no serious adverse reactions. Conclusion The therapeutic effect of nebulized inhalation on asthma in infants and young children is definite. It can shorten the symptom disappearance time and hospitalization time significantly. It has advantages of small dosage and high safety.