目的探讨青少年精神分裂症患者脑CT与精神症状的相关关系。方法对35例青少年精神分裂症患者行脑CT检查,用阳性和阴性症状量表(PANSS)评定观察组的精神症状;脑CT测量患者的脑室值并用哈氏值、脑室指数、第三脑室宽度、侧脑室体部指数、侧脑室宽度指数、前角指数来表示,并与35例健康青少年进行对照。结果观察组脑室宽度和哈氏值都大于对照组,观察组前角指数和脑室指数都小于对照组(P<0.05)。观察组中的阴性症状分值与哈氏值呈正相关性,阴性症状分值与脑室宽度也呈正相关性,阴性症状分值与脑室指数呈负相关性,阴性症状分值与前角指数也呈负相关性(P<0.05)。结论青少年精神分裂症患者存在显著的脑室扩大,且与精神症状尤其是阴性症状相关。 Objective To investigate the relationship between brain CT and mental symptoms in schizophrenia in adolescents. Methods 35 cases of schizophrenia in adolescents with brain CT scan, the positive and negative symptoms scale (PANSS) to assess the observation group’s psychiatric symptoms; brain CT measurement of ventricular volume values ​​and with Hirschsch’s index, ventricular index, third ventricle width , Lateral ventricle body index, lateral ventricular width index, anterior angle index, and 35 healthy adolescents were compared. Results The width of the ventricle and the Hs value of the observation group were larger than those of the control group. The anterior angle index and the ventricular index of the observation group were less than those of the control group (P <0.05). The score of negative symptom in the observation group was positively correlated with the Haste’s value. The score of negative symptom was also positively correlated with the ventricular width. The score of negative symptom was negatively correlated with ventricular index. The score of negative symptom and index of anterior horn were also Negative correlation (P <0.05). Conclusion Adolescent schizophrenia has significant ventricular enlargement and is associated with psychiatric symptoms, especially negative symptoms.