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雷公藤具有防治类风湿性关节炎、肾小球肾炎和多种癌症等卓越疗效,却毒性甚大,严重限制了其临床应用。配伍是中医用药特色,通过恰当配伍可以起到减毒或增效作用。文章着重综述近年来雷公藤配伍减毒的研究进展,并提出些许对策,以期为其配伍安全用药提供参考。
Tripterygium has the excellent curative effect of preventing and treating rheumatoid arthritis, glomerulonephritis and many kinds of cancers, but it is very toxic and severely limits its clinical application. Compatibility is the characteristics of traditional Chinese medicine, through the appropriate compatibility can play an attenuating or synergistic effect. This article focuses on the research progress of reducing the toxicity of Tripterygium wilfordii in recent years, and puts forward some countermeasures so as to provide a reference for its compatibility and safe medication.